Professional and Linguistic Assessments Board (PLAB) Practice Exam

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Prepare for the PLAB Test with comprehensive quizzes. Familiarize yourself with real exam scenarios using flashcards and multiple-choice questions, each accompanied by explanations and tips. Enhance your readiness for success!

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What is the primary side effect of Rifampin in tuberculosis treatment?

Gout
Color blindness
Orange secretions
Peripheral neuropathy

The correct answer is: Orange secretions

Rifampin, a key medication used in the treatment of tuberculosis, is known for causing orange discoloration of bodily secretions. This includes urine, sweat, saliva, and tears. The pigment change occurs due to the drug's ability to induce enzymes that affect the metabolism of other substances, leading to the formation of colored metabolites. This side effect, although striking, is generally harmless and serves as an important reminder for patients to be aware of changes in their secretions while undergoing treatment. It helps in preventing unnecessary concern when patients notice these color changes. The mechanism behind this effect is not completely understood, but it is a well-documented phenomenon associated with rifampin therapy. Understanding this side effect is crucial for patient education, as it can alleviate anxiety regarding changes they might observe during treatment.